From the Buddhist point of view, being in a depressed state, in a state of discouragement, is seen as a kind of extreme that can clearly be an obstacle to taking the steps necessary to accomplish one's goals. A state of self-hatred is even far more extreme than simply being discouraged, and this can be very, very dangerous. For those engaged in Buddhist practice, the antidote to self-hatred would be to reflect upon the fact that all beings, including oneself, have Buddha Nature--the seed or potential for perfection, full Enlightenment--no matter how weak or poor or deprived one's present situation may be. So those people involved in Buddhist practice who suffer from self-hatred or self-loathing should avoid contemplating the suffering nature of existence or the underlying unsatisfactory nature of existence, and instead they should concentrate more on the positive aspects of one's existence, such as appreciating the tremendous potential that lies within oneself as a human being. And by reflecting upon these opportunities and potentials, they will be able to increase their sense of worth and confidence in themselves.

--from The Art of Happiness: A Handbook for Living by His Holiness the Dalai Lama and Howard C. Cutler, M.D.